Stone: Due to the fact that its power deals poison damage (25 points of it, to be exact), the Serpent Stone is the obvious choice for this build. Race: The Poisoner's skillset can mesh reasonably well with most races I recommend Altmer for a boost to the build's magical abilities.
For those of you that don't have it, please note that this build does use the Dragonborn DLC. The Poisoner is a build that utilizes poison damage (and to a lesser extent, Paralysis) in almost all its forms. The reality is, however, that there is a wide variety of options for poison damage in Skyrim. When someone brings up the subject of poison in Skyrim, they’re usually talking about the harmful concoctions that you can make via Alchemy.